Funding by the SNSF 2009 to 2015. Additional support by local foundations and industry.
Excellent patient recruitment: The cohort recruited >3’600 patients into the biomarker cohort, over 1’000 and 100 patients into the interventional COMFORTABLE AMI and imaging IBIS-4 trials, respectively.
Completed event adjudication of first cohort (2’200 patients): The 30 days and 1 year follow-up of 2’200 biomarker patients was completed 10/2013 and independent event adjudication finalized 02/2014.
Large biobank of > 100’000 patient samples: We are assessing expression profiles of inflammatory cells in blood and coronary thrombi and are performing biomarker analyses in blood, serum and plasma.
Excellent local support. This project could be realized thanks to the excellent work of previous and current SPUM fellows, study nurses and the local catheter teams; Zurich SPUM team (Fig. 2).